Testosterone has as much weight as estrogen in the discussion of the body’s wellness. Production of any androgen is essential to the overall functions of the body, including cognition and sexual function. For the body to remain healthy, a balanced amount of both testosterone and estrogen is vital. One of the rising innovations to solve this hormonal imbalance issue is Hormone Replacement Therapy.

Let’s discuss in detail what HRT is and how it affects the testosterone levels in women.

Effect of Hormone Replacement Therapy

Testosterone in Women

There are three main androgens in women: testosterone, androstenedione, and dehydroepiandrosterone (DHEA) or the more abundant metabolite version, which is dehydroepiandrosterone sulphate (DHEAS).

Testosterone and androstenedione are derived from the ovarian and adrenal glands. When a woman reaches reproductive age, testosterone is produced through the mid-cycle surge during ovulation.

While commonly associated as a male hormone, testosterone is actually the most potent of androgens in women. Testosterone levels in females are 1/10 of a male’s, while bioavailable testosterone is even less. Premenopausal females produce little than over 0.5 mg per day of testosterone. As a woman enters menopause, testosterone production decreases slowly as a function of age, with testosterone levels lower in a menopausal female than an ovulating one. This is why, for unclear reasons, a number of women in their 40s experience reduced levels of testosterone that takes place alongside ovulation.

Surgery can also have an impact on a woman’s testosterone levels. Both premenopausal and post-menopausal females who have had ovaries removed have experienced at least 50% decrease in testosterone. The effect is even more pronounced on premenopausal women.

Effects of Low Testosterone in Women

While not the most dominant female hormone, the effects of having very low testosterone are pronounced. Below are some of the effects of low testosterone levels in women:

  • Fatigue
  • Dry or thinning skin
  • Loss of muscle tone
  • Poor tolerance for exercise
  • Anxiety/depression
  • Osteoporosis or bone density loss

HRT to Improve Sexual Functions

When diagnosed with low levels of testosterone, women can be offered the option of testosterone replacement therapy. One benefit of testosterone HRT in women is the improvement of sexual functions and emotions. In fact, testosterone has been revealed as the most significant determinant of these functions.

Published studies reveal that through the introduction of testosterone in women with a deficiency of the hormone through HRT, there has been an improvement of related moods such as:

  • Level of arousal
  • Ability to achieve orgasm
  • Sexual fantasies and desires
  • Masturbation
  • Satisfaction with partner
  • Improved libido

These behaviors were particularly observed in studies sponsored by the Morristown, NJ based Watson Pharmaceuticals. Seventy-five patients who had undergone ovary and uterus removals were either administered with pellets that contained pure estradiol, or estradiol mixed with testosterone. Thirty-four postmenopausal women who received the mixture with testosterone had increased sexual libido compared to their counterparts, while 53 premenstrual women reported improvements in arousal and fantasies. In addition, no serious side effects were monitored during the testing.

Action Mechanisms

The introduction of the hormones testosterone and DHEAS helps stimulate sexual behaviors and moods in two ways:

  • Entrance into a cell’s nucleus and initiating protein synthesis and transcription (via normal steroid action). The positive changes can take weeks before revealing itself.
  • The steroid acts as a neurotransmitter, transmitting signals among each cell. Unlike the former example, the benefits can be seen rapidly, with reports of it coming out in less than an hour with sublingual testosterone).

Get HRT to Address Testosterone Imbalance

Similar to how compounded low-dose naltrexone for multiple sclerosis not yet widespread, testosterone solutions are designed mostly for men, which makes commercially available medications risky for women. That is why natural HRT is highly effective in combatting testosterone deficiency in women. You can get low testosterone-type HRT, which is specifically created by compounding pharmacies to address a patient’s individual condition.

With HRT, replacement testosterone that mimic those of the patients are introduced to the body, and constantly updated to be in sync with the patient’s body condition to work effectively and bring out its benefits.  Before undergoing treatment, however, consult your compounding pharmacy in California to find out if hormone replacement therapy is the best solution for you.

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